Hyperbaric Oxygen Treatment

Credit: Shamir Medical Center

Study discovers hyperbaric oxygen treatments halt the aging of blood cells and reverses the aging process.

A new research study from Tel Aviv University (TAU) and the Shamir Medical Center in Israel suggests that hyperbaric oxygen treatments (HBOT) in healthy aging adults can stop the aging of blood cells and reverse the aging process. In the biological sense, the grownups’ blood cells in fact grow younger as the treatments progress.

The scientists discovered that a distinct protocol of treatments with high-pressure oxygen in a pressure chamber can reverse two significant processes related to aging and its illnesses: the shortening of telomeres (protective areas located at both ends of every chromosome) and the accumulation of old and malfunctioning cells in the body. Concentrating on immune cells including DNA acquired from the participants’ blood, the study found a lengthening of up to 38%of the telomeres, along with a decline of up to 37%in the existence of senescent cells.

The study was led by Teacher Shai Efrati of the Sackler School of Medication and the Sagol School of Neuroscience at TAU and Founder and Director of the Sagol Center of Hyperbaric Medicine at the Shamir Medical Center; and Dr. Amir Hadanny, Chief Medical Research Officer of the Sagol Center for Hyperbaric Medication and Research at the Shamir Medical Center. The medical trial was performed as part of a thorough Israeli research study program that targets aging as a reversible condition.

The paper was published in Aging on November 18, 2020.

” For several years our group has actually been engaged in hyperbaric research study and treatment– treatments based on protocols of exposure to high-pressure oxygen at different concentrations inside a pressure chamber,” Teacher Efrati explains. “Our achievements throughout the years consisted of the improvement of brain functions harmed by age, stroke or brain injury.

” In the present research study we wanted to analyze the impact of HBOT on healthy and independent aging grownups, and to find whether such treatments can decrease, stop or even reverse the normal aging process at the cellular level.”

The scientists exposed 35 healthy individuals aged 64 or over to a series of 60 hyperbaric sessions over a period of 90 days. Each individual supplied blood samples previously, throughout and at the end of the treatments along with a long time after the series of treatments concluded. The scientists then examined different immune cells in the blood and compared the outcomes.

The findings indicated that the treatments really reversed the aging procedure in 2 of its major elements: The telomeres at the ends of the chromosomes grew longer rather of much shorter, at a rate of 20%-38%for the various cell types; and the portion of senescent cells in the total cell population was reduced considerably– by 11%-37ending upon cell type.

” Today telomere shortening is thought about the ‘Holy Grail’ of the biology of aging,” Teacher Efrati states. “Researchers worldwide are attempting to develop medicinal and environmental interventions that enable telomere elongation. Our HBOT procedure was able to accomplish this, showing that the aging process can in reality be reversed at the fundamental cellular-molecular level.”

” Until now, interventions such as lifestyle adjustments and intense exercise were shown to have some inhibiting effect on telomere reducing,” Dr. Hadanny includes. “However in our study, only 3 months of HBOT had the ability to lengthen telomeres at rates far beyond any presently offered interventions or way of life adjustments. With this pioneering study, we have actually opened a door for further research on the cellular impact of HBOT and its potential for reversing the aging process.”

Referral: “Hyperbaric oxygen therapy increases telomere length and reduces immunosenescence in separated blood cells: a potential trial” by Yafit Hachmo, Amir Hadanny, Ramzia Abu Hamed, Malka Daniel-Kotovsky, Merav Catalogna, Gregory Fishlev, Erez Lang, Nir Polak, Keren Doenyas, Mony Friedman, Yonatan Zemel, Yair Bechor and Shai Efrati, 18 November 2020, Aging
DOI: 10.18632/ aging.202188

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